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The Commission is guided by: the Constitution of the Republic of Kazakhstan, the Code of the Republic of Kazakhstan “On the health of the people and the healthcare system”, the State Standards of the Republic of Kazakhstan “Good Laboratory Practice”, “Good Clinical Practice”, the Declaration of Helsinki of the World Medical Organization, the Guidelines for the work of ethics committees conducting examination of biomedical research by the World Health Organization, the European Convention for the Protection of the Rights of Vertebrate Animals Used for Experimental and Other Scientific Purposes, other normative legal acts of the Republic of Kazakhstan in the field of regulation of clinical trials and international declarations, guidelines in the field of research ethics and the Regulations on the local commission on bioethics.

The Commission considers all issues related to the observance of the general principles of humanism, morality and biomedical ethics when reviewing the research plan at the local level.

The Commission is a structural subdivision of the IKTU and operates since January 2022.